Category: General Cardiology

Framingham risk score for CAD incorporates age, gender, total cholesterol, HDL cholesterol, smoking status, systolic BP, and antihypertensive therapy.

Retrospective analysis of intravenous calcium in digitoxicity Conventional wisdom says that intravenous calcium should be avoided in digitoxicity. A retrospective analysis assessed this aspect. Digoxin being a sodium-potassium

The coronary risk reduction after smoking cessation is fifty percent by one year.

Age and etiology of aortic stenosis: degenerative AS beyond 60 years, BCAV stenosis in 40-60 years and rheumatic AS before 40 years of age.

Ten year survival of aortoarteritis (Takayasu’s arteritis) was eighty four percent with sixty four percent was event free survival.

ATP and ADP bind to platelet P2 receptors. The platelet receptors for ADP are P2Y1 and P2Y12 while those from ATP is P2X1.

The presence of hypertension in AS makes it (left ventricle) a double loaded LV with valvular obstruction and vascular resistance presenting dual loads.

RE-LY trial: In patients with AF, dabigatran given at a dose of 110 mg was associated with stroke rates similar to warfarin, but with less major bleeding.

Tripling the dose was found to be useful in those with heterozygous mutation producing clopidogrel resistance, while it was not useful in homozygous cases.

Ticagrelor is an antiplatelet agent belonging to a new class known as cyclopentyl triazolo-pyrimidines (CPTP) acting as a reversible allosteric antagonist.