Increased body mass index has been associated with increased risk of sudden cardiac death. For every five unit increase in BMI there is an associated 16% increased risk
There are several observations which have shown that in the elderly and patients with chronic diseases like heart failure and coronary artery disease, overweight or mild obesity may
Photon-counting computed tomography is a relatively new technology which has several advantages in cardiovascular imaging. Some of the disadvantages of conventional energy-integrating detector CT are taken care of
Genomic effects of aldosterone are those at the nuclear level through transcription after binding to mineralocorticoid receptors. Effects on mineralocorticoid receptors other than those on the nucleus are
REALIZE-K study was a prospective, double-blind, randomized withdrawal trial in heart failure with reduced ejection fraction and prevalent or incident mineralocorticoid receptor antagonist induced hyperkalemia [1]. During the
Mineralocorticoid receptor antagonists are useful for the management of heart failure. But what all are the adverse effects of excess aldosterone in the system? Let us have a
It is well known that serum potassium levels come down with increased aldosterone secretion. That is because aldosterone causes potassium excretion and retention of sodium and water. In
Transthyretin amyloidosis is a progressive disease due to misfolded protein subunits of transthyretin. Normal transthyretin is a tetrameric protein. Abnormal misfolded subunits accumulate as amyloid fibrils in various
Particulate matter air pollution is being recognized as an important cardiovascular risk and many of our cities are having plenty of air pollution. A recent study published in
