Mineralocorticoid Receptors: MCQ

Mineralocorticoid Receptors: MCQ

Mineralocorticoid Receptors are found in all of the following, Except? [1]
A. Liver
B. Colon
C. Hippocampus
D. Kidney

Correct answer : A. Liver

Mineralocorticoid receptors are found in sodium transporting epithelia like that in kidney and colon as well as in nonepithelial tissues like heart and brain [2]. They also have high affinity for glucocorticoids [3].
Aldosterone promotes myocardial fibroblast proliferation and has a role in myocardial fibrosis. This accounts for the beneficial antifibrotic effect of mineralocorticoid receptor antagonists when used in the management of heart failure [4].

References

  1. https://pgblazer.com/mineralocorticoid-receptors-mcq/
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521600/
  3. https://pubmed.ncbi.nlm.nih.gov/15947887/
  4. https://www.frontiersin.org/articles/10.3389/fphar.2021.629818/full