REALIZE-K study was a prospective, double-blind, randomized withdrawal trial in heart failure with reduced ejection fraction and prevalent or incident mineralocorticoid receptor antagonist induced hyperkalemia [1]. During the
Mineralocorticoid receptor antagonists are useful for the management of heart failure. But what all are the adverse effects of excess aldosterone in the system? Let us have a
It is well known that serum potassium levels come down with increased aldosterone secretion. That is because aldosterone causes potassium excretion and retention of sodium and water. In
Transthyretin amyloidosis is a progressive disease due to misfolded protein subunits of transthyretin. Normal transthyretin is a tetrameric protein. Abnormal misfolded subunits accumulate as amyloid fibrils in various
Particulate matter air pollution is being recognized as an important cardiovascular risk and many of our cities are having plenty of air pollution. A recent study published in
Human population is aging globally and the prevalence of calcific aortic stenosis is increasing. Aortic stenosis has now become the most common valvular heart disease in adults. Progressive
Secondary mitral regurgitation is mitral regurgitation in the absence of significant structural abnormalities of the mitral valve. It can be divided into ventricular secondary mitral regurgitation and atrial
Conventional method of permanent pacing in complete heart block involves pacing from the right ventricular apex. Though it is easy to achieve, there is a potential risk of
