LV dysfunction in Ebstein's anomaly

LV dysfunction in Ebstein’s anomaly

LV dysfunction in Ebstein’s anomaly: Left ventricular systolic and diastolic dysfunction have been reported in Ebstein’s anomaly of tricuspid valve, presumably due to the left ventricular fibrosis seen in these cases.¹ Left ventricular fibrosis can be due to arterial oxygen desaturation. Left ventricular non compaction is another potential cause of left ventricular dysfunction in cases in which it is associated.²

In a study from Mayo Clinic, 50 of the 495 patients who underwent surgery for Ebstein’s anomaly had moderate or severe left ventricular dysfunction documented on preoperative echocardiogram.³ Left ventricular function improved in all but four of these patients after surgery. There was no deterioration of left ventricular function after surgery in any of the cases.

Left ventricular diastolic dysfunction in Ebstein’s anomaly could be due to right ventricular volume overload and it can persist even after intracardiac repair.⁴

References

1. Maruo T, Kano S, Ichino K, Imai Y, Asakawa M, Itoh N, Tamiya E, Ikenouchi H, Hada Y. Ebstein’s anomaly associated with left ventricular dysfunction: a case report. J Cardiol. 1998;31 Suppl 1:131-6.
2. Bagur RH, Lederlin M, Montaudon M, Latrabe V, Corneloup O, Iriart X, Laurent F. Images in cardiovascular medicine. Ebstein anomaly associated with left ventricular noncompaction. Circulation. 2008 Oct 14;118(16):e662-4.
3. Brown ML, Dearani JA, Danielson GK, Cetta F, Connolly HM, Warnes CA, Li Z, Hodge DO, Driscoll DJ. Effect of operation for Ebstein anomaly on left ventricular function. Am J Cardiol. 2008 Dec 15;102(12):1724-7.
4. Inai K, Nakanishi T, Mori Y, Tomimatsu H, Nakazawa M. Left ventricular diastolic dysfunction in Ebstein’s anomaly. Am J Cardiol. 2004 Jan 15;93(2):255-8.