Acute aortic regurgitation Clinical scenario of acute aortic regurgitation is quite different from familiar finding in chronic aortic regurgitation. Due to the atypical findings, it may be difficult
GRIPHON Study on Selexipag Selexipag is an orally active IP prostacyclin receptor agonist. It is structurally different from prostacyclin. GRIPHON was a phase 3 double blind randomized, placebo
ISAR-REACT 5 Trial – Review ISAR-REACT 5 Trial [1] was a multicenter study with randomized patients who presented which acute coronary syndrome for whom an invasive strategy was
CULPRIT-SHOCK Clinical Trial – Review Culprit Lesion Only PCI Versus Multivessel PCI in Cardiogenic Shock (CULPRIT-SHOCK) trial investigated two strategies for percutaneous coronary interventions (PCI) in acute myocardial
Third heart sound in health and disease Third heart sound (S3) occurs in early diastole due to rapid deceleration of transmitral blood flow as the ventricles fill [1].
Takayasu arteritis Takayasu arteritis is an inflammatory disorder affecting aorta and its major branches. It is also known as aortoarteritis and pulseless disease [1]. Arteritis leads to thickening
CORAL study on renal artery stenting In the Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL) study, 947 patients who had atherosclerotic renal artery stenosis and either systolic hypertension
Innocent heart murmurs Murmurs without any organic heart disease can be found in children. These have been called by various names like innocent murmur, physiological murmur, normal murmur
Postural orthostatic tachycardia syndrome Postural orthostatic tachycardia syndrome (POTS) is characterized by orthostatic tachycardia in the absence of orthostatic hypotension. Criteria for diagnosis of POTS are as follows: