All About Cardiovascular System and Disorders

PRKAG2 gene which encodes for the gamma-2 regulatory subunit of AMP-activated protein kinase and BMP2 have been implicated in to WPW syndrome.

Loss of expression of PKP2 decreases peak Na current and delayed recovery from inactivation of Na channels, decreasing Na current and conduction velocity, causing conduction block and re-entrant

It is well known that hypokalemia worsens the effect of both congenital and drug-induced long QT syndrome.

Severity of symptoms as well as the QT interval could be correlated with genetic variations in nitrous oxide synthetase adaptor protein (NOS1AP).

Early repolarization has been considered as benign ECG change, till a couple of studies published in 2008 in leading journals caught the attention of the cardiovascular fraternity.

ECG showing NSVT - salvo of ventricular premature complexes

Cumulative stress due to repeated stressful events over time without de-stressing or healing can erode coping mechanisms and cause break down.

Professionals with type A personality have a higher risk for cardiac events.

The natriuretic peptides are the A type, B type, C type and the D type.

Midregional pro-atrial natriuretic peptide (MR-proANP) is a stable fragment of prohormone of atrial natriuretic peptide.