Stent thrombosis in the setting of surgery Stent thrombosis is a serious complication, which is more likely with drug eluting stents (DES) than bare metal stents (BMS). This
Drugs with reversible anti platelet action While the antiplatelet actions of clopidogrel and prasugrel are irreversible, that of the following drugs are reversible: Dipyridamole Cilostazol NSAIDS (non steroidal
Withholding anti platelet therapy in those with coronary stents Five to ten percent of patients who have been implanted a coronary stent will need a surgery within the
Reversible and irreversible platelet inhibition by anti platelet agents Agents which irreversibly inhibit platelets are: Aspirin Ticlopidine Clopidogrel Prasugrel In general all these agents except prasugrel are ideally
Cardiovascular surgeries with high risk of bleeding: Re-do surgeries Surgeries in the setting of infective endocarditis Coronary artery bypass grafting after failed percutaneous coronary intervention – bail out
Factors promoting stent thrombosis following surgery The most important factor promoting stent thrombosis following non cardiac surgery is the withdrawal of antiplatelet agents. Another important factor is that
Urine albumin creatinine ratio predicts cardiovascular events Urine albumin creatinine ratio (UACR) is known to predict cardiovascular events. Elevated urine albumin creatinine ratio would mean at least low
Modified Carpentier functional classification of mitral valve disease Modified Carpentier functional classification of mitral valve disease: Carpentier in 1983 described a classification, mainly for mitral regurgitation, from the
ECG changes in pulmonary embolism ECG changes in pulmonary embolism: The commonest finding on electrocardiogram in pulmonary embolism is sinus tachycardia. Pulmonary embolism can occur without significant electrocardiographic
Genetic beta-blockade: GRK5 polymorphism is thought to inhibit beta-adrenergic receptor signaling and thereby acts as a form of 'genetic beta-blockade'
